After finally taking her family to Dubai through sheer determination and hard work, Vagelyn finds herself looking for someone to fill the gap inside her heart. Following several attempts in dating, she reconnects with high school batchmate and notorious bully, Janwell. Brushing aside their interactions online as mere coincidence, Vagelyn soon realizes the possibility of turning their budding relationship into a life-long commitment.
Despite his numerous rejections and failures, Carlo's perseverance and determination eventually lead him to make a name for himself in the showbiz industry as JC Alcantara.
After her heart got broken for the second time because of her boyfriend Gio's incessant infidelity, Karla finds a new reason to be happy upon reconnecting with her former classmate, Ralph. Convinced that he is the right one for her, Karla fights for their love amid her family's and friends' concern about her boyfriend's baggage. Ralph's insecurities, however, begin to put a rift on their relationship, leaving Karla back to square one. A realization soon dawns upon her while she tries to pick herself back up.
Bert instantly forms a friendship with Dodong and takes him under his wing as soon as he finds out his family situation. Despite hating his father Ismael for leaving their family, a strong urge to avenge him engulfs Bert after the former was brutally murdered. Bent on giving justice to his father, his brother Rey's preaching about forgiveness falls on deaf ears until Bert finds himself on death's doorstep. However, the pain of his past haunts him when he finally reunites with Dodong while threading on the spiritual path.
Janice is happily living her dream with her boyfriend Eddie until his mother Corsing enters the picture and frowns on their relationship. Upon building a new life with Eddie, Janice moves heaven and earth just to please Corsing, who remains hostile towards her daughter-in-law as her way to spare Eddie from possible heartbreak. Although a series of unfortunate incidents befalls her family, Janice’s efforts soon begin to finally pay off.
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Rebecca was a hard-working woman in just unusual command by her family in a rural province, since her life became low since she had been argued by her siblings bout their share on allowances and personal problems, will she ever complied to achieve her better goals to live in his foreign spice?
Petrus is a blind person who had ability to make choices to help by staying as close to his brother Raddy although some disadvantages occurred once she made unhonorable needs when he married and no one wondered for when he will cast his dignity.
Ivy loves to act on stage but she agreed to put it on hold when her boyfriend Ian asked her to when he proposed marriage so that they can have children. But Ivy was unable to return to acting even after having four children as Ian continued to forbid her. Sacrificing her passion, Ivy set up a school with her husband. Even as she followed a new path in life, the two continued to fight, which eventually resulted in their separation. Ivy was able to pursue acting again with the help of her children and the teachers in her school. This is when she met Carl, a young theater actor whom Ivy had to mentor. Despite their 16 year age gap, Ivy fell in love and took a risk by having a relationship with him.
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Zaldy and Jex work as chefs in an airline catering services company. Jex has a longtime crush on Zaldy and not wasted time asking him out. But to her disappointment, Zaldy keeps rejecting her invitation. As Jex leaves the company to look for greener pastures, the two eventually lose touch with each other only to reconnect years later after failed relationships. It doesn't take long before they eventually start dating. As the pandemic was brewing, the two decide to push through with their planned trip to Baguio. With their more-than-friends, less-than-lovers status, the two find themselves stuck together indefinitely in the city as Luzon is put into lockdown.
Larcy's world gets crushed when she learns about her husband Jun's affair with Rose, with whom he has a child named Ryan. But instead of leaving him, Larcy decides to make a sacrifice to make her family complete again. When she learns that the woman has decided to leave Jun, Larcy offers to take care of their son. But her effort does not pay off as their relationship continues to fall apart. Nevertheless, she has no regrets about loving Ryan. Things eventually get complicated when Rose comes back after many years to take Ryan back.
Jann Mar forgets about his fear of rejection to find his estranged biological father, only to be dejected in the end. Armed with his stepfather’s advice, JM finally follows his heart as he tries his luck in “Tawag ng Tanghalan.”
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The story tells about the first Philippine Olympic Gold Medalist Hidilyn Diaz's sake to pursuing her goals to her dreams as a weightlifter in the history of Philippine sports, she was among the 5 siblings of a family living in Zamboanga in which are strike on poverty, and her passion was to join the said sport in order to make herself put of difficult living, since she was participating in international meets and earned better income, she tries her best to get the Olympic medal but until in 2016 in Rio Games she got her bag full of silver.
Valerie dreams of a better life with her siblings, Ali and Cha, until her brother follows the footsteps of their father Lando. As the cracks of their relationship widen, their love for their family drives them to find their way back together.
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Tanch's efforts pay off when a devout Sarah decides to follow her heart. Things get complicated as Juan, the father of Tanch's son, demands something that drives a wedge between the two. As Sarah tries to move on, a realization dawns on her.
Edwin follows in his family's footsteps of earning a living through illicit ways. Amid his degree, he sticks with his old habits in the US until he returns to the Philippines. As he makes things right, he finds the meaning of his life in tattooing.