In Birmingham, biker paramedic Mark Hayes desperately battles to keep a man alive after a heart attack in the street, while colleague Steve races to help an epileptic who is having a fit. In Essex, biker cop PC 'Stomp' Allum is stalking the roads on an unmarked bike when he has to open the throttle to catch joy-riders racing at over 100mph.
Essex biker cop Lucy Watson has her hands full with a drunk in Southend, and PC Steve Clements has an insurance mystery to solve.
Lucy Watson is called in to help when a man is reportedly seen wielding an axe, and a mother is caught breastfeeding her baby in a moving car. Mark Hayes helps a prisoner who has fallen ill, Steve Harris deals with an intoxicated patient and the paramedics rush to a pedestrian who has been hit by a bus
A child involved in a road accident for a second time receives help from Steve Harris, while Mark deals with someone having a seizure, but suspects the situation is not all it appears to be. Martin Ackers impounds a woman's vehicle and a diabetic in Oxford requires a rapid response.
Mark Hayes deals with an aggressive drunk in Birmingham's city centre, while officers in Essex crack down on uninsured vehicles and unlicensed drivers. Steve Harris is called to a pregnant woman in extreme pain and Oxford paramedics rush to an old lady who has taken a heavy fall.
A driver needs airlifting to hospital, and the biker paramedics are called in to action to save a man's life.
The Essex team goes after insurance dodgers, a North Yorkshire cop lectures a driver, and the Birmingham paramedics race to two serious incidents.
Biker paramedic Mark deals with the 10-year-old victim of a hit-and-run and biker cops go undercover on the trail of boy racers.
Paramedic Steve Harris deals with the harrowing case of a toddler with a serious head injury, and Mark Hayes assists a collapsed teenager with Crohn's disease.
The bikers treat a playground head injury, and deal with an argumentative driver, a faulty truck and a man with a rare medical condition.