Exterminator Billy Bretherton leaves Louisiana behind and brings his skills to the wilds of the Great White North.
A new mother calls Billy after a wild canine snatches her dog and is hunting her other pets. When Billy's trap is too small for the job, he suits up and throws down in a no holds barred cage match with one of the North's most feared predators. Early spring brings a baby boom, as critters get busy in attics and garages. Billy then teams up with trapper Ben for a dawn to dusk eviction of ferocious squatters who won't go without a fight.
Billy stakes out a northern farm where a predator is creating a horror show at a chicken coop. Later: he goes north to help remove a group of beavers who dammed up a creek and washed out the local road.
Billy heads to cottage country where a houseboat rental company finds a nest of snakes inside one of their boats. Billy and his exterminator partner Derick jump into the serpent moshpit and attempt to break up the slithering party.
Billy responds to a construction site where a vicious varmint has the tradespeople running scared. He tries to outsmart the beast, and takes some brutal bites in the process. And strange paranormal activity jeopardizes the sale of a country home, so Billy enlists his reluctant dispatcher Bea to investigate. They go in prepared for a ghost hunt, and get more than they bargained for.
With a gang of wild turkeys tearing apart a country wedding venue, a stressed-out wedding planner calls on Billy to puts the bride's big day back on track. But the birds prove to be more agile than anticipated. What ensues is a comedy of errors as Billy and his partner, Terry, try to put this poultry in its place! Then a trio of Vietnamese Centipedes with a nasty nature and a serious bite is on the loose in a basement apartment! Billy puts himself in the line of fire to keep a family safe.
Billy gets a call from a terrified family with three young children. There's a honey bee nest inside their house! Billy calls on his buddy Ian, a local beekeeper, to help him move the angry bees to a happy place, but the colony doesn't go quietly. Billy suffers a few stings while struggling to get the upper hand. Then Billy has to dodge talons and beak to hand-catch a Great Horned Owl that's stuck in a family's rural home.
Billy gets called to a quiet suburban neighborhood where an unassuming home has been converted into a reptile rooming house. The dangerous rescue mission requires Billy to wrestle crocs, serpents and lizards and hand them over to a sanctuary. Then, further up north, Billy gets help from local trapper, Mike, to take charge of a couple of prickly porcupine cottage-squatters that need to get gone!
Billy is asked to round up a group of ostriches that escaped from a farm. Also: first-time house flippers call on Billy to eradicate a severe rat infestation in their home.
A reptile invades a nature lover's pool and Billy is called in to try and remove it. Later: he tackles an apartment home infested with bedbugs.
Billy helps a magician after his animals run amok during a show at a retirement home. Later: he visits a maple syrup-maker who is plagued by a skunk.
A prank gets out of hand when fraternity brothers get a goat in their house and Billy is tasked with removing it. Later: Billy faces flying squirrels that have invaded a family's attic.
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