Derren visits the Valley of Fire, Nevada, where he makes the sun disappear and then shows viewers how he did it. He conducts the same experiment on a group of people in Hollywood, Barcelona and London, and Matt Lucas is dumbfounded by a card trick.
Derren tries to manipulate the thoughts of athlete Kelly Holmes at a north London running track - with fascinating results. He also attempts to implant notions into the dreams of a sleeping student.
Derren uses his powers of misdirection and illusion to win a blindfolded noughts and crosses game in London, and finds water divining in the Nevada desert is thirsty work. A group of strangers invited onto the show find they all have something in common.
Derren sets out to get two people communicating with each other despite speaking different languages and performs a routine spanning the canals of Venice. He also invites Robbie Williams to a remote location in the East End for a spot of body piercing.
Derren travels to Vienna, where he performs a perplexing effect on the giant Ferris wheel featured in Orson Welles' The Third Man. He also manipulates a cinema audience to forget a film they have just watched, while Stephen Merchant takes part in a game of fifty-fifty chance.
Derren performs an old séance trick for Meera Syal, makes an amputee feel sensation in their missing limb and demonstrates a memory feat in Monaco.