Jools welcomes Isle of Wight duo Wet Leg, US singer and blues guitarist Joe Bonamassa, Nigerian-born, London-based artist Obongjayar and BRIT School alumni and south Londoner Cat Burns to the show.
Jools is joined by rock‘n’roll legend Liam Gallagher, Dubliner and debutante Sinead O'Brien, Belgian duo Charlotte Adigéry and Bolis Pupul, and Malian singer Oumou Sangaré.
Jools welcomes actress and singer Jessie Buckley and guitarist Bernard Butler, south Londoner Poppy Ajudha, electro-pop quartet Confidence Man, and rock'n'roll band Warmduscher to the show.
Jools welcomes London musician Koyej Radical, Leicester band Kasabian, north west Londoner Knucks, jazz singer Judi Jackson and south London poet, novelist and songwriter Kae Tempest to the show.
Jools welcomes Scottish singer-songwriter Paolo Nutini, breakthrough artist Katy J Pearson, producer William Orbit and singer Polly Scattergood, Parisian twins Ibeyi and Oxford indie rockers Foals.
Jools welcomes Florence + The Machine, The Mysterines, Kamal, Deyaz and Jamie T to the show, as well as celebrating Sir Paul McCartney's eightieth birthday with a look through the archives.